Hirotaka Matsuo Selected Research

urate transporter

7/2022	Urate Transporter ABCG2 Function and Asymptomatic Hyperuricemia: A Retrospective Cohort Study of CKD Progression.
11/2021	Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A12.
7/2020	Dysfunctional ABCG2 gene polymorphisms are associated with serum uric acid levels and all-cause mortality in hemodialysis patients.
1/2020	Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice.
11/2018	Effects of Osthol Isolated from Cnidium monnieri Fruit on Urate Transporter 1.
11/2017	Functional non-synonymous variants of ABCG2 and gout risk.
1/2017	GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.
4/2016	Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.
1/2016	The effects of URAT1/SLC22A12 nonfunctional variants, R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression.
1/2014	Identification of a hypouricemia patient with SLC2A9 R380W, a pathogenic mutation for renal hypouricemia type 2.

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Hirotaka Matsuo Research Topics

Disease

44	Gout 06/2022 - 12/2008
18	Hyperuricemia 07/2022 - 12/2011
10	Neoplasms (Cancer) 06/2022 - 03/2002
6	Renal hypouricemia 08/2021 - 04/2005
4	Parkinson Disease (Parkinson's Disease) 01/2022 - 03/2015
4	Arthritis (Polyarthritis) 11/2021 - 01/2019
4	Breast Neoplasms (Breast Cancer) 01/2018 - 01/2014
4	Glioma (Gliomas) 08/2012 - 03/2002
2	Metabolic Diseases (Metabolic Disease) 01/2020 - 12/2011
2	Acute Kidney Injury (Acute Renal Failure) 01/2014 - 12/2008
2	Hyperplasia 09/2007 - 02/2006
1	Phototoxic Dermatitis (Phototoxicity) 07/2021
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021
1	Body Weight (Weight, Body) 01/2019
1	Chronic Disease (Chronic Diseases) 01/2019
1	Fibrosarcoma 01/2018
1	Intestinal Diseases (Diseases, Intestinal) 11/2017
1	Diabetes Mellitus 04/2016
1	Reperfusion Injury 01/2016
1	Hypertension (High Blood Pressure) 01/2016
1	Hypoxia (Hypoxemia) 01/2016
1	Gastroenteritis 01/2016
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2016
1	Ulcer 07/2015
1	Infections 01/2015
1	Urolithiasis 01/2014
1	Glioblastoma (Glioblastoma Multiforme) 01/2013
1	Obesity 12/2011
1	Poisoning 11/2010
1	Carbon Monoxide Poisoning (Poisoning, Carbon Monoxide) 11/2010

Drug/Important Bio-Agent (IBA)

43	Uric Acid (Urate)IBA 07/2022 - 04/2005
12	urate transporterIBA 07/2022 - 04/2005
8	Proteins (Proteins, Gene)FDA Link 07/2022 - 09/2007
7	Amino Acid Transport Systems (Amino Acid Transporter)IBA 04/2010 - 03/2002
4	Member 2 Subfamily G ATP Binding Cassette TransporterIBA 07/2020 - 01/2014
3	Large Neutral Amino Acid-Transporter 1IBA 04/2010 - 07/2007
3	AntigensIBA 08/2006 - 03/2002
2	Coffee FDA Link 06/2022 - 01/2022
2	Organic Anion TransportersIBA 01/2022 - 01/2014
2	ATP-Binding Cassette Transporters (ABC Transporters)IBA 11/2021 - 01/2014
2	oxidized low density lipoproteinIBA 04/2020 - 01/2019
2	ORALIT (ORS)IBA 10/2019 - 04/2016
2	CholesterolIBA 01/2019 - 04/2016
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 04/2016
2	Glutamic Acid (Glutamate)FDA Link 04/2016 - 01/2013
2	AntioxidantsIBA 01/2016 - 03/2015
2	Protein Kinases (Protein Kinase)IBA 01/2015 - 08/2012
2	Leucine (L-Leucine)FDA Link 01/2014 - 08/2012
2	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2014 - 12/2008
1	AlkaloidsIBA 06/2022
1	HLA-DRB1 Chains (HLA DRB1)IBA 01/2022
1	PorphyrinsIBA 07/2021
1	nanaomycin KIBA 01/2021
1	Singlet OxygenIBA 08/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2020
1	Antimalarials (Antimalarial Agents)IBA 08/2020
1	Superoxides (Superoxide)IBA 08/2020
1	Colchicine FDA LinkGeneric 01/2019
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2019
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2019
1	Alanine Transaminase (SGPT)IBA 01/2019
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2019
1	InflammasomesIBA 01/2019
1	LDL CholesterolIBA 01/2019
1	osthol (osthole)IBA 11/2018
1	PotassiumIBA 01/2018
1	Adenosine Triphosphate (ATP)IBA 11/2017
1	Blood Group Antigens (Blood Groups)IBA 11/2017
1	glutamyl-glutamic acid (Glu-Glu)IBA 01/2017
1	histidylhistidine (His-His)IBA 01/2017
1	Free RadicalsIBA 01/2016
1	Intergenic DNA (Junk DNA)IBA 01/2016
1	ProteomeIBA 01/2016
1	Protein Deglycase DJ-1IBA 07/2015
1	Parasympatholytics (Antispasmodics)IBA 07/2015
1	Protein Isoforms (Isoforms)IBA 07/2015
1	Antitussive Agents (Antitussives)FDA Link 07/2015
1	Biomarkers (Surrogate Marker)IBA 07/2015
1	Anti-Infective Agents (Microbicides)IBA 01/2015
1	Local Anti-Infective Agents (Antiseptics)IBA 01/2015
1	Myosins (Myosin)IBA 01/2015
1	Cyclic GMP-Dependent Protein Kinase Type IIIBA 07/2014
1	LigandsIBA 04/2014
1	Glutathione (Reduced Glutathione)IBA 01/2013
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 08/2012
1	Phosphotransferases (Kinase)IBA 08/2012
1	Mitogen-Activated Protein KinasesIBA 08/2012
1	Essential Amino AcidsIBA 08/2012
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 08/2012
1	Cytostatic AgentsIBA 08/2012
1	UDPglucose-Hexose-1-Phosphate Uridylyltransferase (Galactose 1 P Uridyltransferase)IBA 08/2012
1	ethyl acetateIBA 12/2011
1	Myelin Basic ProteinIBA 11/2010

Therapy/Procedure

5	Therapeutics 01/2019 - 09/2002
1	Biological Therapy 01/2019
1	Traditional Medicine (Folk Remedies) 11/2018
1	Renal Dialysis (Hemodialysis) 01/2016
1	Radiotherapy 01/2013
1	Drug Therapy (Chemotherapy) 01/2013